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Create an assembly graph with the reference as template.
Take each read and match it to graph segments. Add new nodes if a part does not match.
Keep track how many reads support each path segment and determine the most likely paths.
Build haplotype sequences from likely paths.
The text was updated successfully, but these errors were encountered:
For an active region:
Create an assembly graph with the reference as template.
Take each read and match it to graph segments. Add new nodes if a part does not match.
Keep track how many reads support each path segment and determine the most likely paths.
Build haplotype sequences from likely paths.
The text was updated successfully, but these errors were encountered: