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SELF-CALIBRATING ANALYSIS OF STORM DATA

dSTORM microscopy can improve the resolution of conventional fluorescent microscopy by one order of magnitude. The data analysis software has to localize many thousand single molecule point-spread-functions to reconstruct an image of the underlying structure.

Content of this archive: storm/ sources for single-molecule-localization and command-line utility to analyze .sif and .hdf5 input data gui/ Qt-based graphical-user-interface (GUI) for selection of input files and appropriate parameter(s) python/ helper scripts to analyze and display the coordinate lists generated by the utilities above colorcomposer/ multi-channel measurements have to be aligned due to chromatic aberrations. Tetraspeck-Beads are detected automatically so that the images can be registrated easily.

A manual is in doc/doc.pdf.

See INSTALL for instructions on how to build and install storm or storm-gui from scratch.

Download binaries for Windows 64-bit from http://hci.iwr.uni-heidelberg.de/Software/simpleSTORM-win64.zip

More algorithmic details are available in the diploma thesis at http://hci.iwr.uni-heidelberg.de/Staff/jschleic/

Copyright 2010-2013 by Ullrich Koethe, Joachim Schleicher, Frank Herrmannsdoerfer and Ilia Kats

Please direct questions, bug reports, and contributions to ullrich.koethe (AT) iwr.uni-heidelberg.de

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Data processing software for dSTORM super-resolution microscopy

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